1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin

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1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin is a polychlorinated dibenzo-p-dioxin (PCDD) congener. 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin can cause pale (fatty) livers, gastrointestinal hemorrhage and early death in H/W and line A rats at the highest dose (10,000 μg/kg). 1,2,3,4,7,8-Hexachlorodibenzo-p-dioxin also induces sinusoidal distension, and even severe peliosis in line B.

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